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    <!-- http://www.ebi.ac.uk/efo/EFO_0000478 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0000478">
        <rdfs:label>obsolete_esophageal adenocarcinoma</rdfs:label>
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        <oboInOwl:hasDbXref>OMIM:109350</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>esophageal adenocarcinoma</oboInOwl:hasExactSynonym>
        <ns6:IAO_0000115>A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.</ns6:IAO_0000115>
        <oboInOwl:hasExactSynonym>esophagus adenocarcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>adenocarcinoma of the esophagus</oboInOwl:hasExactSynonym>
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        <oboInOwl:hasDbXref>ONCOTREE:ESCA</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>Orphanet:99976</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10:C15.2</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>oesophageal adenocarcinoma</oboInOwl:hasExactSynonym>
        <ns3:reason_for_obsolescence>Replaced by Mondo term MONDO_0005028, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0005028</ns3:reason_for_obsolescence>
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        <oboInOwl:hasDbXref>DOID:4914</oboInOwl:hasDbXref>
        <ns6:IAO_0100001>http://purl.obolibrary.org/obo/MONDO_0005028</ns6:IAO_0100001>
        <oboInOwl:hasDbXref>NCIT:C4025</oboInOwl:hasDbXref>
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