obsolete_hereditary spastic paraplegia true X-linked Recessive Hereditary Spastic Paraplegia X linked Recessive Hereditary Spastic Paraplegia Spastic Paraplegia, Hereditary Paraplegia, Spastic, Hereditary Hypertrophic Motor-Sensory Neuropathy-Spastic Paraplegia Hereditary X Linked Recessive Spastic Paraplegia Type V, HMSN HMSN V Strumpell disease HSMN V Autosomal Dominant Spastic Paraplegia Hereditary OMIM:600361 Spastic Paraplegia-Hypertrophic Motor-Sensory Neuropathy Autosomal Dominant Hereditary Spastic Paraplegia true Spastic Paraplegia, Hereditary, Autosomal Recessive Hereditary sensory-motor neuropathy, type V (disorder) 2.46 ICD9:334.1 Use http://www.orpha.net/ORDO/Orphanet_685 label : hereditary spastic paraplegia HERED SPASTIC PARAPLEGIA Spastic Paraplegia, Hereditary, X-Linked Recessive Autosomal Recessive Spastic Paraplegia, Hereditary Spastic Paraplegia, Hereditary, Autosomal Dominant Hereditary, Spastic Paraplegia, X-Linked Recessive Hereditary Motor Sensory Neuropathy with Pyramidal Signs Hereditary, Spastic Paraplegia, Autosomal Dominant Hereditary Spastic Paraplegia, Autosomal Recessive HMSN V (Hereditary Motor and Sensory Neuropathy Type V) Tomasz Adamusiak Strumpell-Lorrain disease X-Linked, Spastic Paraplegia, Hereditary Hereditary spastic paraplegia (disorder) SNOMEDCT:76043009 HSP - Hereditary spastic paraplegia http://www.orpha.net/ORDO/Orphanet_685 Spastic Paraplegia, Autosomal Recessive, Hereditary DOID:2476 Hereditary Autosomal Recessive Spastic Paraplegia Hereditary sensory-motor neuropathy, type V Paraplegia, Hereditary Spastic Hypertrophic Motor Sensory Neuropathy Spastic Paraplegia Type V Hereditary Motor and Sensory Neuropathy Spastic Paraplegias, Hereditary Paraplegias, Hereditary Spastic Spastic Paraplegia, X-Linked Recessive, Hereditary Hereditary motor and sensory neuropathy type V SNOMEDCT:39912006 Spastic Paraplegia, Autosomal Dominant, Hereditary MESH:D015419 Spastic Paraplegia Hypertrophic Motor Sensory Neuropathy A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8) Hereditary Autosomal Dominant Spastic Paraplegia HMSN Type V Hereditary motor and sensory neuropathy, type V James Malone Hereditary Spastic Paraplegias Hereditary X-Linked Recessive Spastic Paraplegia Familial spastic paraplegia syndrome Autosomal Recessive Hereditary Spastic Paraplegia Spastic congenital paraplegia spastic paraplegia Hereditary Motor-Sensory Neuropathy with Pyramidal Signs Spastic paraplegia with hypertrophic sensory-motor neuropathy, type V