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    <!-- http://www.ebi.ac.uk/efo/EFO_0000765 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0000765">
        <rdfs:label>obsolete_AIDS</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
        <ns2:gwas_trait rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</ns2:gwas_trait>
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        <oboInOwl:hasDbXref>ICD10:B20</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Acquired Immuno-Deficiency Syndromes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MedDRA:10001509</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Immuno-Deficiency Syndrome, Acquired</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Immuno-Deficiency Syndromes, Acquired</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Immunodeficiency due to human immunodeficiency virus infection</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000117>James Malone</ns3:IAO_0000117>
        <oboInOwl:hasExactSynonym>Acquired human immunodeficiency virus infection syndrome NOS</oboInOwl:hasExactSynonym>
        <ns2:obsoleted_in_version>3.88.0</ns2:obsoleted_in_version>
        <oboInOwl:hasExactSynonym>acquired immune deficiency syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acquired Immune deficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Acquired immune deficiency syndrome (AIDS)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ACQUIRED IMMUNODEFIC SYNDROME</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MESH:D000163</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:62479008</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin&amp;amp;apos;s lymphoma and Kaposi&amp;amp;apos;s sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Acquired Immuno-Deficiency Syndrome</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000115>A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV).  It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes.  Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea.  Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin&#39;s lymphoma and Kaposi&#39;s sarcoma).  The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood. -- 2004</ns3:IAO_0000115>
        <ns3:IAO_0100001>http://purl.obolibrary.org/obo/MONDO_0012268</ns3:IAO_0100001>
        <oboInOwl:hasExactSynonym>Syndrome, Acquired Immuno-Deficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ACQUIRED IMMUNE DEFIC SYNDROME</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Acquired Immuno Deficiency Syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ACQUIRED IMMUNO DEFIC SYNDROME</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000115>A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin&#39;s lymphoma and Kaposi&#39;s sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>AIDS - Acquired immunodeficiency syndrome</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000115>An HIV infectious disease that is a characterized cytologically by a reduction in the numbers of CD4-bearing helper T cells to 20 percent or less of normal thereby rendering the subject highly vulnerable to life-threatening conditions (as Pneumocystis carinii pneumonia) and to some that become life threatening (as Kaposi&#39;s sarcoma) and that is caused by infection with HIV commonly transmitted in infected blood especially during illicit intravenous drug use and in bodily secretions (as semen) during sexual intercourse.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Acquired immune deficiency syndrome, NOS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>IMMUNOL DEFIC SYNDROME ACQUIRED</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acquired human immunodeficiency virus infection syndrome NOS (disorder)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIt:C2851</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>AIDS (disorder)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Syndromes, Acquired Immuno-Deficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>AIDS, ACQUIRED IMMUNODEFICIENCY SYNDROME</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Immunodeficiency Syndromes, Acquired</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Acquired immunodeficiency syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Acquired immune defic. syndr.</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Acquired Immunodeficiency Syndromes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>AIDS, NOS</oboInOwl:hasExactSynonym>
        <ns2:reason_for_obsolescence>Replaced by Mondo term MONDO_0012268, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0012268</ns2:reason_for_obsolescence>
        <oboInOwl:hasExactSynonym>Acquired immunodeficiency syndrome, NOS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Immunodeficiency Syndrome, Acquired</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>DOID:635</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Syndromes, Acquired Immunodeficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Immunologic Deficiency Syndrome, Acquired</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Acquired immune deficiency syndrome (AIDS) (disorder)</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000115>Acquired immunodeficiency syndrome is a HIV infection consisting of a disease of the human immune system that is characterized cytologically especially by a reduction in the numbers of CD4-bearing helper T cells to 20 percent or less of normal thereby rendering the subject highly vulnerable to life-threatening conditions (as Pneumocystis carinii pneumonia) and to some that become life threatening (as Kaposi&#39;s sarcoma) and that is caused by infection with HIV commonly transmitted in infected blood especially during illicit intravenous drug use and in bodily secretions (as semen) during sexual intercourse.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>acquired immunedeficiency syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Syndrome, Acquired Immunodeficiency</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000115>An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.</ns3:IAO_0000115>
        <ns3:IAO_0000115>A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per µL of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_agent Human immunodeficiency virus 1 or has_agent Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>IMMUNODEFIC SYNDROME ACQUIRED</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ACQUIRED IMMUNODEFICIENCY SYNDROME, AIDS</oboInOwl:hasExactSynonym>
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