obsolete_acute megakaryoblastic leukaemia https://rarediseases.info.nih.gov/diseases/524/acute-megakaryoblastic-leukemia true ONCOTREE:AMKL FAB M7 megakaryocytic myelosis EFO:0003025 MESH:D007947 AMKL Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia (AML) that occurs predominantly in childhood and particularly in children with Down syndrome (DS-AMKL). Nonspecific symptoms may be irritability, weakness, and dizziness while specific symptoms include pallor, fever, mucocutaneous bleeding, hepatosplenomegaly, neurological manifestations and rarely lymphadenopathy. Acute panmyelosis with myelofibrosis may also be associated with AMKL. In contrast to DS-AMKL (around 80 % survival), non-DS-AMKL is an AML subgroup associated with poor prognosis. UMLS:C0023462 acute megakaryoblastic leukemia, FAB M7 ICD9:207.2 NCIT:C3170 http://purl.obolibrary.org/obo/MONDO_0018872 leukemia, megakaryocytic, malignant Orphanet:518 acute megakaryocytic leukemia 3.88.0 acute myeloid leukemia M7 acute megakaryoblastic leukaemia, FAB M7 SCTID:277602003 thrombocytic leukaemia acute megakaryoblastic leukemia (FAB type M7) megakaryocytic leukemia DOID:8761 AML M7 acute megakaryoblastic leukemia GARD:0000524 acute megakaryoblastic leukaemia acute myeloblastic leukemia type 7 Replaced by Mondo term MONDO_0018872, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0018872 ICDO:9910/3 Wikipedia:Acute_megakaryoblastic_leukemia acute megakaryocytic leukemias ICD10:C94.20 acute M7 myeloid leukemia ICD10:C94.2