obsolete_dental caries true true Replaced by Mondo term MONDO_0005276, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0005276 Dental Decay ICD9:521.0 Dental White Spot WHITE SPOT DENT CARIES DENT Caries, Dental Tomasz Adamusiak Spot, White caries ICD10:K02 DECAY DENT http://purl.obolibrary.org/obo/MONDO_0005276 MedDRA:10012318 NCIt:C52593 Decay, Dental DENT WHITE SPOT Dental White Spots DENT WHITE SPOTS WHITE SPOTS DENT DOID:216 White Spots DENT DECAY MESH:D003731 SNOMEDCT:80967001 Spots, White White Spot, Dental White Spot White Spots, Dental 3.88.0 DENT CARIES Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. The three most prominent theories used to explain the etiology of the disease are that acids produced by bacteria lead to decalcification; that micro-organisms destroy the enamel protein; or that keratolytic micro-organisms produce chelates that lead to decalcification.