is_about insulin-like growth factor-binding protein 1 protein measurement IGFBP-1 measurement true http://www.uniprot.org/uniprot/P08833 Dani Welter IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.