realizes has_participant role_of ribonucleic acid analyte role RNA assay sequencer assay by sequencer GRO-seq Global run-on sequencing Genomic run-on sequencing Amy Tang GRO-seq or Genomic run-on sequencing or sometimes Global run-on sequencing is a sequencing assay based on traditional nuclear run-on assays, but instead of looking at a few loci at a time, this is a high-throughput method that allows for the calculation of transcription rates of all genes across the genome. Please note that the starting materials for sequencing are RNAs, not genomic DNA because nascent transcripts are studied.