neoplasm dysplasia true A usually neoplastic transformation of the cell, associated with altered architectural tissue patterns. The cellular changes include nuclear and cytoplasmic abnormalities. Molecular genetic abnormalities are also often found and, in some instances, may lead to cancer. Laura Huerta dyscrasia dysplasia Dysplasia is a term used in pathology to refer to an abnormality of development or an epithelial anomaly of growth and differentiation (epithelial dysplasia). MedDRA:10058314 NCIt:C4086 dysplastic UMLS:C0334044 SNOMEDCT:25723000