metopic craniosynostosis true SNOMEDCT:109409003 metopic synostosis Laura Huerta interfrontal craniofaciosynostosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413823/ Metopic craniosynostosis is the early fusion of the forehead (frontal) bones. It accounts for 5%–15% of all craniosynostosis cases. This premature fusion of the frontal bones results in a characteristically altered skull shape, termed trigonocephaly, that usually requires surgical correction. Rare genetic bone disease Genetic cranial malformation Rare genetic bone development disorder