Ataxia-oculomotor apraxia type 4 Ataxia-oculomotor apraxia-4 is an autosomal recessive neurologic disorder characterized by onset of dystonia and ataxia in the first decade. Additional features include oculomotor apraxia and peripheral neuropathy. Some patients may show cognitive impairment. The disorder is progressive, and most patients become wheelchair-bound in the second or third decade (summary by Bras et al., 2015). Hannah McLaren OMIM:616267 AOA4 Orphanet:459033 Rare hereditary ataxia Early-onset ataxia with dementia Spinocerebellar ataxia with oculomotor anomaly