chronic kidney disease stage 5 chronic kidney disease true MedDRA:10014647 Baron Koylass End stage renal failure A degree of kidney failure severe enough to require dialysis or kidney transplantation for survival characterized by a severe reduction in glomerular filtration rate (less than 15 ml/min/1.73 m2) and other manifestations including increased serum creatinine. HP:0003774 chronic renal failure MedDRA:10077512 UMLS:C2316810 End stage renal disease SNOMEDCT:433146000 End-stage renal failure end-stage renal disease