eye degenerative disorder autosomal recessive disease hereditary optic neuropathy hereditary optic atrophy autosomal recessive optic atrophy Term added in response to Mondo restructuring. To be considered for replacement or obsoletion in EFO also. Orphanet:98676 A rare hereditary optic atrophy characterized by an early onset of bilateral optic nerve degeneration without other systemic features. Clinical manifestations include pallor of the optic disks, severe but slowly progressing visual impairment, and in some patients also paracentral scotoma, photophobia and dyschromatopsia. UMLS:CN229293