hereditary cardiac anomaly familial patent arterial duct Term added in response to Mondo restructuring. To be considered for replacement or obsoletion in EFO also. UMLS:CN242171 Orphanet:466729 Familial patent arterial duct is a rare, genetic, non-syndromic, congenital anomaly of the great arteries characterized by the presence of an isolated patent arterial duct (PDA) (i.e. failure of closure of ductus arteriosis after birth) in several members of the same family. vascular anomaly