realizes role_of deoxyribonucleic acid analyte role DNA assay assay by high throughput sequencer CUT&Tag AI agent Aleix Puig CUT&Tag stands for cleavage under targets and tagmentation and is a chromatin profiling method that uses antibody-targeted tagmentation to map the locations of specific proteins, histone modifications, or transcription factors on DNA. The method involves binding an antibody to the protein target of interest, then recruiting protein A-Tn5 transposase fusion protein which cleaves and inserts sequencing adapters into DNA adjacent to the antibody-bound target (tagmentation). The tagmented DNA fragments are then amplified and sequenced using high-throughput sequencing. CUT&Tag offers improved signal-to-noise ratios and requires fewer cells compared to ChIP-seq. CUT&Tag sequencing