<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://www.ebi.ac.uk/efo/EFO_0920053"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/"
     xmlns:efo="http://www.ebi.ac.uk/efo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0004009 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004009">
        <rdfs:label>has primary input</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_71196 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_71196">
        <rdfs:label>glucagon-like peptide-1 receptor agonist</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0009410 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0009410">
        <rdfs:label>response to xenobiotic stimulus</rdfs:label>
    </Class>
    


    <!-- http://www.ebi.ac.uk/efo/EFO_0920053 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0920053">
        <rdfs:label xml:lang="en">response to GLP-1 receptor agonist</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0009410"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004009"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_71196"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasBroadSynonym>response to incretin mimetic</oboInOwl:hasBroadSynonym>
        <ns3:IAO_0000115>A physiological or pathological response to exposure to a glucagon-like peptide-1 (GLP-1) receptor agonist. GLP-1 receptor agonists are a class of incretin-mimetic drugs that bind to and activate the GLP-1 receptor, stimulating glucose-dependent insulin secretion, suppressing glucagon release, delaying gastric emptying, and promoting satiety. This response encompasses glycemic control outcomes including HbA1c reduction, body weight changes, and other metabolic effects observed following GLP-1 receptor agonist treatment.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>GLP-1 receptor agonist response</oboInOwl:hasExactSynonym>
        <rdfs:seeAlso>https://github.com/EBISPOT/efo/issues/2562</rdfs:seeAlso>
        <oboInOwl:hasRelatedSynonym>GLP-1RA response</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>glucagon-like peptide-1 receptor agonist response</oboInOwl:hasExactSynonym>
        <ns3:IAO_0000117>AI agent</ns3:IAO_0000117>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



