transient viral transduction method adenovirus transduction 2026-03-26T11:30:00Z adenoviral vector Transient transfection method involving the transgene introduction into the cells of interest using engineered adenoviral particles. Adenoviral particles can transduce both replicating and non-dividing cells. Adenoviral DNA does not integrate into the host genome, but rather, resides episomally in the host nucleus. PMID:28944281 AI agent A transient viral transduction method that uses adenoviral vectors to deliver nucleic acid cargo into target cells, where the viral DNA persists as an episomal element without integrating into the host genome.