non-viral transfection method lipofection 2026-03-26T11:30:00Z Lipofection is a liposome-based transfection technique whereby the nucleic acid is encapsulated within a phospholipid vesicle that can either directly fuse with cell membranes or be endocytosed by a cell, allowing delivery of the genetic material to the cell. AI agent A non-viral transfection method in which cationic lipid formulations spontaneously form complexes with negatively charged nucleic acids and fuse with the cell membrane to deliver the nucleic acid cargo into target cells. PMID:33976969 MI:0717