has modifier Chronic leukemia myeloproliferative disorder chronic disease Chronic Eosinophilic Leukemia, Not Otherwise Specified EFO:1000178 A rare myeloproliferative neoplasm characterized by a clonal proliferation of eosinophilic precursors resulting in persistently increased numbers of eosinophils in the blood, marrow and peripheral tissues. Since acute eosinophilic leukemia is at best exceedingly rare, the term eosinophilic leukemia is normally used as a synonym for chronic eosinophilic leukemia. In cases in which it is impossible to prove clonality and there is no increase in blast cells, the diagnosis of "idiopathic hypereosinophilic syndrome" is preferred. (WHO, 2001) NCIT:C4563 CEL/hypereosinophilic syndrome ONCOTREE:CELNOS ICDO:9964/3 CEL eosinophilic leukemia chronic eosinophilic leukemia, not otherwise specified chronic eosinophilic leukemia/hypereosinophilic syndrome CELNOS chronic eosinophilic leukemia