obsolete_Eccrine Porocarcinoma https://rarediseases.info.nih.gov/diseases/7431/eccrine-porocarcinoma true 3.88.0 UMLS:C1266065 DOID:7566 GARD:0007431 SCTID:254708001 http://purl.obolibrary.org/obo/MONDO_0006189 NCIT:C5560 ICDO:8409/3 MESH:D057090 eccrine porocarcinoma eccrine porocarcinoma of skin epidermotropic eccrine carcinoma malignant eccrine poroma porocarcinoma porocarcinoma/spiroadenocarcinoma EFO:1000229 ONCOTREE:POCA Replaced by Mondo term MONDO_0006189, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0006189 A carcinoma with eccrine differentiation arising from the sweat glands. It may arise de novo or as a malignant transformation of a pre-existing poroma. It usually grows in the legs, buttocks, feet, and trunk and usually presents as an ulcerative plaque. It is characterized by the presence of intraepidermal and dermal nests of malignant epithelial cells. It may recur after excision and metastasize to the lymph nodes and less frequently to distal anatomic sites.