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    <!-- http://www.ebi.ac.uk/efo/EFO_1000318 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_1000318">
        <rdfs:label>obsolete_Langerhans Cell Histiocytosis</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
        <deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</deprecated>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving lymph nodes of multiple sites</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:604856</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Lch</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of intrapelvic lymph nodes</oboInOwl:hasExactSynonym>
        <ns5:reason_for_obsolescence>Replaced by Mondo term MONDO_0018310, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0018310</ns5:reason_for_obsolescence>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving lymph nodes of head, face and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of head, face and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICDO:9753/1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>histiocytosis X</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving lymph nodes of inguinal region and lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Langerhan&#39;s cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>GARD:0006858</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:277.89</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9754/3</oboInOwl:hasDbXref>
        <ns5:obsoleted_in_version>3.88.0</ns5:obsoleted_in_version>
        <oboInOwl:hasDbXref>ONCOTREE:LCH</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:65399007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10:C96.6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0019621</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10:C96.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MedDRA:10069698</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of head, face and/or neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Orphanet:389</oboInOwl:hasDbXref>
        <ns4:IAO_0100001>http://purl.obolibrary.org/obo/MONDO_0018310</ns4:IAO_0100001>
        <oboInOwl:hasRelatedSynonym>Langerhans-cell histiocytosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving lymph nodes of axilla and upper limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICD10:C96.0</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of axilla and upper limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of intrathoracic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving intrathoracic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of inguinal region and lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Langerhans cell histiocytosis, NOS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of multiple sites</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Langerhans cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICDO:9751/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9751/3</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of intra-abdominal lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0432552</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0432553</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0432550</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0432551</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0432554</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:202.5</oboInOwl:hasDbXref>
        <rdfs:comment>We follow NCIT in classifying this as a neoplasm but this may be revisited</rdfs:comment>
        <oboInOwl:hasExactSynonym>Langerhans cell granulomatosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>DOID:2571</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C3107</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving intra-abdominal lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>COHD:4278365</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of axilla and/or upper limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>LCH</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0432549</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0432547</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving intrapelvic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0432548</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving lymph nodes of head, face, and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICDO:9752/1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of spleen</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Langerhans cell histiocytosis, Not otherwise specified</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease of lymph nodes of inguinal region amd/or lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>letterer-Siwe disease involving spleen</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EFO:1000318</oboInOwl:hasDbXref>
        <skos:exactMatch rdf:resource="http://identifiers.org/meddra/10069698"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/mesh/D006646"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/omim/604856"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/110450007"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/118614007"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/128809007"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/128811003"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/128812005"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/154583006"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/154773005"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/188654004"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/188655003"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/188659009"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/190955000"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/190956004"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/190960001"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/234439008"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/236957004"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/267510005"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/269628007"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/366059005"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/snomedct/65399007"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/snomedct/67574008"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0019621"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432547"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432548"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432549"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432550"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432551"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432552"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432553"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0432554"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_2571"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C3107"/>
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