obsolete_Nevus of Ito true EFO:1000395 GARD:0010830 Ito's Nevus http://purl.obolibrary.org/obo/MONDO_0016985 ICD10:D22.6 3.88.0 hypomelanosis of Ito nevus of Ito UMLS:C0022283 Orphanet:263432 NCIT:C7582 UMLS:CN202288 Nevus of Ito is a benign dermal melanocytosis occurring most frequently in the Asian populations and characterized by unilateral, asymptomatic, blue, gray or brown skin pigmentation within the acromioclavicular and upper chest area (involving the side of the neck, the supraclavicular and scapular areas, and the shoulder region). It is usually diagnosed in early infancy and in early adolescence. Nevus of Ito may progressively enlarge and darken in color (particularly with puberty) and its appearance usually remains stable once adulthood is reached. Spontaneous regression does not occur. Malignant melanoma has rarely been reported within a nevus of Ito. It shares the clinical features of nevus of Ota, except its anatomic location and may in rare occasions occur together with the latter. Nevus fuscocaeruleus acromiodeltoideus nevi of Ito Replaced by Mondo term MONDO_0016985, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0016985