obsolete_aortic valve prolapse true 3.88.0 DOID:5232 Aortic Valve Prolapse MedDRA:10057454 MESH:D001023 Replaced by Mondo term MONDO_0006655, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0006655 http://purl.obolibrary.org/obo/MONDO_0006655 Sirarat Sarntivijai The downward displacement of the cuspal or pointed end of the trileaflet AORTIC VALVE causing misalignment of the cusps. Severe valve distortion can cause leakage and allow the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to aortic regurgitation.