obsolete_brain edema true http://purl.obolibrary.org/obo/MONDO_0006684 DOID:4724 MedDRA:10006121 Brain Edema 3.88.0 MESH:D001929 intracranial swelling wet brain Sirarat Sarntivijai Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6) Replaced by Mondo term MONDO_0006684, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0006684