obsolete_encephalomalacia true NCIt:C98920 http://purl.obolibrary.org/obo/MONDO_0006741 Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75) Encephalomalacia DOID:2034 3.88.0 Encephalomalacia (disorder) Replaced by Mondo term MONDO_0006741, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0006741 Sirarat Sarntivijai MESH:D004678 SNOMEDCT:58762006 MedDRA:10051818