obsolete_euthyroid sick syndrome true Conditions of abnormal THYROID HORMONES release in patients with apparently normal THYROID GLAND during severe systemic illness, physical TRAUMA, and psychiatric disturbances. It can be caused by the loss of endogenous hypothalamic input or by exogenous drug effects. The most common abnormality results in low T3 THYROID HORMONE with progressive decrease in THYROXINE; (T4) and TSH. Elevated T4 with normal T3 may be seen in diseases in which THYROXINE-BINDING GLOBULIN synthesis and release are increased. Sirarat Sarntivijai 3.88.0 MedDRA:10015549 Euthyroid Sick Syndromes Replaced by Mondo term MONDO_0006755, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0006755 http://purl.obolibrary.org/obo/MONDO_0006755 DOID:2856 MESH:D005067 Sick-euthyroid syndrome (disorder) ICD9:790.94 Euthyroid sick syndrome NCIt:C113170