obsolete_Pelger-Huet anomaly true Autosomal dominant anomaly characterized by abnormal ovoid shape GRANULOCYTE nuclei and their clumping chromatin. Mutations in the LAMIN B receptor gene that results in reduced protein levels are associated with the disorder. Heterozygote individuals are healthy with normal granulocyte function while homozygote individuals occasionally have skeletal anomalies, developmental delay, and seizures. Replaced by Mondo term MONDO_0008214, with which this term was previously merged. Use: http://purl.obolibrary.org/obo/MONDO_0008214 http://purl.obolibrary.org/obo/MONDO_0008214 3.88.0 DOID:9631 MESH:D010381 Sirarat Sarntivijai NCIt:C85002 MedDRA:10029377 Pelger-Huet Anomaly