<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://www.ebi.ac.uk/efo/EFO_1001466"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://www.ebi.ac.uk/efo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.ebi.ac.uk/efo/gwas_trait"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part_of</rdfs:label>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://www.ebi.ac.uk/efo/EFO_0000784 -->

    <ObjectProperty rdf:about="http://www.ebi.ac.uk/efo/EFO_0000784">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has_disease_location</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/MONDO_0005328 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0005328">
        <rdfs:label>eye disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0005364 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0005364">
        <rdfs:label>Graves disease</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000970 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000970">
        <rdfs:label>eye</rdfs:label>
    </Class>
    


    <!-- http://www.ebi.ac.uk/efo/EFO_1001466 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_1001466">
        <rdfs:label>Graves ophthalmopathy</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005328"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005364"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://www.ebi.ac.uk/efo/EFO_0000784"/>
                <someValuesFrom>
                    <Class>
                        <unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000970"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000970"/>
                            </Restriction>
                        </unionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <ns3:gwas_trait rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</ns3:gwas_trait>
        <ns4:IAO_0000117>Gautier Koscielny</ns4:IAO_0000117>
        <oboInOwl:hasExactSynonym>Congestive Ophthalmopathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Myopathic Ophthalmopathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Edematous Ophthalmopathy</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Graves&#39; orbitopathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Thyroid-Associated Ophthalmopathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MESH:D049970</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>thyroid eye disease (TED)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>dysthyroid/thyroid-associated orbitopathy (TAO)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Graves&#39; ophthalmopathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Dysthyroid Ophthalmopathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Thyroid-Associated Ophthalmopathies</oboInOwl:hasExactSynonym>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



