inflammation systemic inflammatory response syndrome true ICD9:995.9 SIRS is a serious condition related to systemic inflammation, organ dysfunction, and organ failure. It is a subset of cytokine storm, in which there is abnormal regulation of various cytokines. SIRS is also closely related to sepsis, in which patients satisfy criteria for SIRS and have a suspected or proven infection. MESH:D018746 Wikipedia:Systemic_inflammatory_response_syndrome Gautier Koscielny NCIt:C94832 MedDRA:10051379 SNOMEDCT:238149007 SIRS Sepsis Syndrome Inflammatory Response Syndrome, Systemic