has part has part has_part has_component has component characteristic of part of inheres in part of quality quality abnormal brain hypoxia brain hypoxia Hypoxia, Brain MESH:D002534 Sirarat Sarntivijai hypoxia of brain MedDRA:10006127 SNOMEDCT:389088001 A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.