Malformation syndrome with skin/mucosae involvement Choroidal atrophy - alopecia Regional choroidal atrophy and alopecia Choroidal atrophy - alopecia is a very rare ectodermal dysplasia syndrome, characterized by the association of choroidal atrophy (sometimes regional), together with other ectodermal dysplasia features including fine and sparse hair, absent or decreased lashes and eyebrows, and possibly mild visual loss and dysplastic/thick/grooved nails. Moloney syndrome orphanet Rare genetic skin disease