22q11.2 microduplication syndrome ICD10:Q92.3 Duplication 22q11.2 Trisomy 22q11.2 Dup(22)(q11) OMIM:608363 orphanet The newly described 22q11.2 microduplication syndrome (dup22q11 syndrome) is the association of a broad clinical spectrum and a duplication of the region that is deleted in patients with DiGeorge or velocardiofacial syndrome (DG/VCFS; see this term), establishing a complementary duplication syndrome. Partial autosomal trisomy/tetrasomy