Genetic susceptibility to infections due to particular pathogens Herpetic encephalitis ICD10:G05.1* Herpes simplex encephalitis Herpetic encephalopathy (HSE) is caused by Herpes simplex virus (HSV) and affects the frontal and temporal lobes, resulting in personality changes, cognitive impairment, aphasia, seizures, and focal weakness. The disease is potentially fatal. OMIM:610551 HSV encephalitis OMIM:613002 OMIM:616532 OMIM:614850 orphanet OMIM:617900 OMIM:614849 Herpes simplex neuroinvasion ICD10:B00.4+