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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://www.orpha.net/ORDO/Orphanet_181387 -->

    <Class rdf:about="http://www.orpha.net/ORDO/Orphanet_181387">
        <rdfs:label>Rare disorder with hypogonadotropic hypogonadism</rdfs:label>
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    <!-- http://www.orpha.net/ORDO/Orphanet_2250 -->

    <Class rdf:about="http://www.orpha.net/ORDO/Orphanet_2250">
        <rdfs:label>Hyposmia - nasal and ocular hypoplasia - hypogonadotropic hypogonadism</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://www.orpha.net/ORDO/Orphanet_181387"/>
        <oboInOwl:hasDbXref>OMIM:603457</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>This syndrome is characterized by the association of severe nasal hypoplasia, hypoplasia of the eyes, hyposmia, hypogeusia and hypogonadotropic hypogonadism.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Bosma-Henkin-Christiansen syndrome</oboInOwl:hasExactSynonym>
        <ns4:definition_citation>orphanet</ns4:definition_citation>
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