obsolete_Hypohidrotic ectodermal dysplasia true ectodermal dysplasia 1, Anhydrotic DOID:14793 Replaced with Mondo term. hypohidrotic X-linked ectodermal dysplasia Hypohidrotic ectodermal dysplasia (HED) is a genetic disorder of ectoderm development characterized by malformation of ectodermal structures such as skin, hair, teeth and sweat glands. It comprises three clinically almost indistinguishable subtypes with impaired sweating as the key symptom: Christ-Siemens-Touraine (CST) syndrome (X-linked), autosomal recessive (AR), and autosomal dominant (AD) HED, as well as a fourth rare subtype with immunodeficiency as the key symptom (HED with immunodeficiency). CST syndrome GARD:0000076 SCTID:239007005 ectodermal dysplasia, hypohidrotic NCIT:C84562 DOID classifies this as a subtype of Clouston disease but this seems to be a confusion re hidrotic vs hypohidrotic ICD10:Q82.4 anhidrotic ectodermal dysplasia 3 3.41.0 Orphanet:238468 anhidrotic ectodermal dysplasia 1 HP:0007607 EDA hypohidrotic ectodermal dysplasia http://purl.obolibrary.org/obo/MONDO_0016535 ectodermal dysplasia anhidrotic anhidrotic ectodermal dysplasia HED