renal tubule disorder Genetic renal tubular disease Osteopetrosis with renal tubular acidosis orphanet Carbonic anhydrase 2 deficiency Marble brain disease Osteopetrosis with renal tubular acidosis is a rare disorder characterized by osteopetrosis (see this term), renal tubular acidosis (RTA), and neurological disorders related to cerebral calcifications. OMIM:267200 ICD10:Q78.2 Mixed RTA MESH:C536058 Renal tubular acidosis type 3 Mixed renal tubular acidosis Guibaud-Vainsel syndrome OMIM:259730 Primary bone dysplasia