Tyrosinemia type 2 Richner-Hanhart syndrome Tyrosinemia due to tyrosine aminotransferase deficiency Tyrosinemia type 2 is an inborn error of tyrosine metabolism characterized by hypertyrosinemia with oculocutaneous manifestations and, in some cases, intellectual deficit. MedDRA:10069463 orphanet ICD10:E70.2 Tyrosinemia type II Oculocutaneous tyrosinemia OMIM:276600 Tyrosinemia due to TAT deficiency Keratosis palmoplantaris - corneal dystrophy Disorder of phenylalanin or tyrosine metabolism Autosomal recessive disease with focal palmoplantar keratoderma as a major feature Metabolic disease with corneal opacity