participates_in has_component has component vitamin metabolic process inborn vitamin metabolic disorder abnormal Rare genetic parathyroid disease and phosphocalcic metabolism disorder Hypocalcemic vitamin D-dependent rickets Pseudovitamin D-deficient rickets OMIM:600081 PDDRI 1-alpha-hydroxylase deficiency VDDR-I Vitamin D-dependency type I Vitamin D dependent rickets type I VDDI Hypocalcemic vitamin D-dependent rickets (VDDR-I) is an early-onset hereditary vitamin D metabolism disorder characterized by severe hypocalcemia leading to osteomalacia and rachitic bone deformations, and moderate hypophosphatemia. OMIM:264700 ICD10:E55.0 orphanet Primary bone dysplasia with defective bone mineralization