obsolete_Neurodegeneration with brain iron accumulation due to C19orf12 mutation true OMIM:614298 3.41.0 ICD10:G23.0 NBIA due to C19orf12 mutation orphanet MPAN Neurodegeneration with brain iron accumulation type 5 http://purl.obolibrary.org/obo/MONDO_0013674 NBIA5 Mitochondrial membrane Protein-Associated Neurodegeneration (MPAN), also known as neurogeneration with brain iron accumulation (NBIA) due to C19orf12 mutations, is an autosomal recessive neurodegenerative disorder characterized by iron accumulation in specific regions of the brain, usually the basal ganglia, associated with slowly progressive pyramidal (spasticity) and extrapyramidal (dystonia) signs, motor axonal neuropathy, optic atrophy, cognitive decline, and neuropsychiatric abnormalities. Mitochondrial membrane protein associated neurodegeneration Replaced with Mondo term.