Partial bilateral aplasia of the Müllerian ducts Genetic renal or urinary tract malformation Mayer-Rokitansky-Küster-Hauser syndrome Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome describes a spectrum of Mullerian duct anomalies characterized by congenital aplasia of the uterus and upper two thirds of the vagina in otherwise phenotypically normal females. It can be classed as either type I (classical) MRKH or type II (atypical) MRKH (also known as MURCS association; see these terms), depending on if it is isolated or associated with other malformations. MedDRA:10065148 OMIM:277000 MRKH syndrome orphanet Rokitansky syndrome ICD10:Q51.8 OMIM:601076 OMIM:158330 Female infertility due to an implantation defect of genetic origin