obsolete_Tangier disease true UMLS:C0039292 Tangier disease (TD) is a rare lipoprotein metabolism disorder characterized biochemically by an almost complete absence of plasma high-density lipoproteins (HDL), and clinically by liver, spleen, lymph node and tonsil enlargement along with peripheral neuropathy in children and adolescents, and, occasionally, cardiovascular disease in adults. ATP-binding cassette transporter A1 deficiency OMIM:205400 orphanet MESH:D013631 Defective adenosine triphosphate-binding cassette transporter A1 Analphalipoproteinemia ICD10:E78.6 http://purl.obolibrary.org/obo/MONDO_0008783 3.41.0 MedDRA:10051875 Replaced with Mondo term.