obsolete_PENS syndrome true PENS syndrome Replaced with Mondo term. UMLS:CN203735 papular epidermal nevi with skyline basal cell layers syndrome Orphanet:313936 PENS syndrome is a rare, genetic, neurocutaneous syndrome characterized by the presence of randomly distributed, small, white to yellowish, multiple, rounded or irregular polycyclically-shaped, epidermal keratotic papules and plaques of ''gem-like'' appearance with a rough surface, typically located on the trunk and proximal limbs, associated with variable neurological abnormalities, including psychomotor delay, epilepsy, speech and language impairment and attention deficit-hyperactivity disorder. Clumsiness, dyslexia and oftalmological abnormalities have also been reported. 3.41.0 http://purl.obolibrary.org/obo/MONDO_0017785