obsolete_Brooke-Spiegler syndrome true Bss OMIM:605041 DOID:0050693 SCTID:703531009 ICD9:239.2 3.41.0 http://purl.obolibrary.org/obo/MONDO_0011512 GARD:0010179 Brooke-Spiegler syndrome (BSS) is an inherited predisposition syndrome presenting with skin appendage tumors, namely cylindromas, spiradenomas and trichoepitheliomas. A minority of patients can also get major and minor salivary glands neoplasms, usually membranous basal cell adenoma. UMLS:C1857941 Replaced with Mondo term. Some consider Brooke-Spiegler syndrome (BSS), familial cylindromatosis (FC), and multiple familial trichoepithelioma (MFT) as phenotypic variations of a single defect, see PMID:16922728 CYLD cutaneous syndrome Brooke-Spiegler syndrome Spiegler-Brooke syndrome Orphanet:79493 BRSS