thalassemia Rare constitutional anemia Alpha-thalassemia DOID:1099 MedDRA:10043390 alpha-Thalassemia Gautier Koscielny UMLS:C1456873 synonyms and doid and parent Alpha-thalassemia is an inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture depending on the number of affected alleles. OMIM:604131 Alpha thalassaemia orphanet ICD10:D56.0 UMLS:C0002312 alpha thalassemia α-thalassemia MESH:D017085 Hematological disorder with renal involvement