obsolete_Cockayne syndrome type 2 true ICD10:Q87.8 3.41.0 OMIM:133540 orphanet OMIM:216400 UMLS:C0751038 http://purl.obolibrary.org/obo/MONDO_0019570 Cockayne syndrome type 2 (CS2) is the severe form of Cockayne syndrome (see this term) presenting at birth and is characterized by neonatal growth failure, severely reduced or absent neurological development, eye abnormalities, arthrogryposis or early postnatal spinal contractures (kyphosis, scoliosis) and often fatal before the age of 7. CS2 clinically overlaps with the COFS syndrome (see this term), the prenatal extreme form of CS. Replaced with Mondo term.