progeroid syndrome Malformation syndrome with skin/mucosae involvement Polymalformative genetic syndrome with increased risk of developing cancer Genetic photodermatosis Xeroderma pigmentosum variant ICD10:Q82.1 orphanet OMIM:278750 UMLS:C0432328 XPV MESH:C536766 UMLS:C1848410 Xeroderma pigmentosum variant is a milder subtype of xeroderma pigmentosum (XP; see this term), a rare genetic photodermatosis characterized by severe sun sensitivity and an increased risk of skin cancer.