has part has part has_part realized in realized in metabolic process disease course Rare constitutional anemia Congenital dyserythropoietic anemia type II Congenital dyserythropoietic anemia type II (CDA II) is the most common form of CDA (see this term) characterized by anemia, jaundice and splenomegaly and often leading to liver iron overload and gallstones. ICD10:D64.4 CDA type 2 SEC23B-CDG CDA type II CDA II UMLS:C1306589 Hereditary erythroblastic multinuclearity with a positive acidified-serum test (hempas) Congenital dyserythropoietic anemia type 2 OMIM:224100 orphanet