obsolete_Chandler syndrome true ICD10:H21.1 Chandler syndrome, the most frequent clinical variant of iridocorneal endothelial (ICE) syndrome (see this term), is characterized by very few iris abnormalities but more severe corneal edema and less severe secondary glaucoma than seen in the other two ICE syndrome variants: Cogan-Reese syndrome and essential iris atrophy (see these terms). orphanet MedDRA:10057487 UMLS:C0544008 Replaced with Mondo term. http://purl.obolibrary.org/obo/MONDO_0020369 3.41.0