Schizencephaly true 2009-12-06T08:05:54Z SNOMEDCT_US:38353004 SNOMEDCT_US:253159001 The presence of a cleft in the cerebral cortex unilaterally or bilaterally, usually located in the frontal area. Schizencephaly is an uncommon malformation of cortical development that results in a cleft, lined by polymicrogyria, that extends from the ependyma of the ventricles to the pia mater. The majority of clefts are posterior frontal or parietal, but temporal or occipital location can occur. MSH:D065707 HP:0010636 human_phenotype UMLS:C0266484 peter Malformations of Cortical Development