substance-related disorder substance withdrawal syndrome drug withdrawal MESH:D013375 substance withdrawal syndrome NCIT:C35046 withdrawal disorder withdrawal syndrome DOID:0060001 A substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of an addictive substance, e.g. opioids, barbiturates and alcohol; amphetamines or similarly acting sympathomimetics; cocaine; nicotine; sedatives, hypnotics, or anxiolytics. Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions. SCTID:363101005 EFO:0005800 drug withdrawal syndrome UMLS:C0152128 substance withdrawal disorder substance withdrawal ICD9:292.0 MONDO:0005567