low-grade astrocytoma diffuse astrocytoma fibrillary astrocytoma (histologic variant) low-grade diffuse astrocytoma NCIT:C7173 astrocytoma, diffuse, malignant A low-grade (WHO grade II) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified. WHO grade II astrocytoma protoplasmic astrocytoma (histologic variant) MONDO:0016686 diffuse astrocytoma low-grade astrocytoma, NOS GARD:0005907 grade II astrocytic tumor grade II astrocytoma Orphanet:251595 astrocytoma, diffuse ICD10:C71.9 UMLS:C0280785 grade II astrocytic neoplasm gemistocytic astrocytoma (histologic variant) ONCOTREE:DASTR grade II glioma